Researchers and the data collection staff working with the Swedish National Study on Aging and Care (SNAC) met at Djurönäset, Stockholm, during a two-day retreat on 24–25 May 2022. During the retreat, examples of 20-year-long outstanding research activity were presented. Moreover, researchers and the data collection staff had the unique opportunity to discuss jointly about future challenges and lines of action. We also had the honor to have Mårten Lagergren with us, the promoter of the SNAC project by the beginning of the 2000s. After 20 years, we are well aware that the SNAC study is more relevant than ever, thanks to the relevance, comprehensiveness and long follow-up of the collected data. SNAC has been, is and will be key to answer some of the key priority challenges concerning the health and well-being of older people.